Bruker Introduces Novel HDX Solution for Protein Conformation Studies
San Antonio, Texas, June 6, 2016 – At ASMS 2016, Bruker today announced a new Hydrogen Deuterium Exchange (HDX) workflow on Bruker’s new HDX Solution™. The Bruker HDX Solution enables an automated and reliable HDX-MS workflow combining the LEAP H/D-X PAL™(LEAP Technologies, part of the Trajan family) with Bruker’s market-leading ultra-high mass resolution maXis II ETD UHR-QTOF system, and the Sierra Analytics HDExaminer software. The Bruker HDX Solution delivers correct monoisotopic accurate-mass assignments for quantitative results from H/D ratios, which enables ready access to biomolecular structural insights with greater certainty and confidence.
Photo from Bruker: Key components of the robotic setup for automatic HX-MS experiments
ARC Future Fellow and Chief Investigator at the ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Professor Michael Breadmore, has spent his research career working to simplify and speed up the analysis of chemical and biological samples, with an increasing emphasis on miniaturization.