Microsampling
It’s about enabling samples to be taken that would or could not otherwise be taken, to drive information rich decision making.
- Microsampling - the why? the what? and the how?
- Our technologies
- Your applications
- Your partner
- Our collaborators
- Blog
- Resources
“Why do we take so much blood, particularly from the frail when we need so little! It’s unethical.” - Neil Spooner, Spooner Bioanalytical, CPSA Colloquia, 25 October 2017.
- The why
- The what
- The how
- Our technologies
- Your applications
- Your partner
- Our collaborators
- Blog
- Resources
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The why - a convergence of factors:
- Patient centric sampling
- Personalized measurement
- Cost burden of healthcare and move to decentralization
- Drive to population and longitudinal studies leading to big data
- Transition of more sensitive and selective analytical techniques into clinical pathology
This means that microsampling must evolve – it is the foundation...
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The what
We started with blood and skin.
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The how
Our mission is to provide easy-to-use tools that enable the remote and minimally invasive collection of biological samples, that are affordable and preserve sample integrity, whilst being simply integrated in to current laboratory workflows.
“Why do we take so much blood, particularly from the frail when we need so little! It’s unethical.” - Neil Spooner, Spooner Bioanalytical, CPSA Colloquia, 25 October 2017.
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Technologies
hemaPEN
The proposed concept of hemaPEN® is a novel blood collection and dispensing platform in dried blood spot (DBS) format. It integrates end-to-end capillary with pre-punched DBS paper for blood collection and dispensing. It exemplifies the advantages of DBS micro-sample stability, while addressing the associated limitations of volumetric accuracy, hematocrit effect and sample integrity.
The proposed concept of the hemaPEN platform technology is expected to provide easy, and more convenient sampling process for dried blood spot (DBS) collection.
More information at hemaPEN.
Microbiopsy
While traditional biopsies collect a chunk of skin several millimetres across, this microbiopsy device takes only a very small skin sample, removing the need for anaesthesia and sutures and leaving only a pinprick-like wound behind.
"It takes only a quarter of a millimetre of skin – or 1,500 cells – for molecular diagnosis, which eliminates the unnecessary excision of suspicious benign lesions and alleviates the fear of excisions that many people have in the diagnostic process." - Professor H Peter Soyer
More information at Minimizing trauma of skin biopsies - Trajan and UniQuest to form partnership for the commercialization and continued development of devices for microsampling human tissue.
The hemaPEN is under development and the prototype device is supplied for research or investigational purposes only. This device is not for therapeutic or diagnostic use.
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Applications
- Clinical trials
- Therapeutic drug monitoring
- Skin cancer detection
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Complete solutions in microsampling
Pipeline of technology for potential integration
- Accurate and precise volumetric liquid measurements
- hemaPEN (capillary collection)
- Sample integrity and stability leveraging dried blood spot technology
- Integration of current DBS best practice (PKI226, Whatman 903)
- Novel porous materials and chemistries for analyte stability
- Fatty acids
- Sample separation
- Novel porous materials for blood separation
Partner in vertically integrated solutions
- Accurate and precise volumetric liquid measurements
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Our collaborators
ASTech
We are working with ASTech - ARC Training Centre for Portable Analytical Separation Technologies on hemaPEN and sample separation.UniQuest, University of Queensland
We are working with UniQuest, University of Queensland (UQ) to develop and commercialize devices for microsampling human tissue.More information about UQ Dermatology Research Centre.
Future Industries Institute, University of South Australia
We are working with the Future Industries Institute (FII) at University of South Australia (UniSA) on microbiopsy development.
Design + Industry
Trajan collaborated with D+I (Design + Industry) in the development of hemaPEN® from initial concepts to prototype device for research and investigational use.Spooner Bioanalytical Solutions
Spooner Bioanalytical Solutions is consulting to Trajan by way of providing expert review, advice and opinion in the area of microsampling. -
Blogs
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Resources
