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Bridging the HDX gap with Monash and Trajan

Bridging the HDX gap with Monash and Trajan

Monash University has recently implemented Trajan's HDX Extended System within its Proteomics and Metabolomics Platform (MPMP), forging a collaborative effort aimed at not only harnessing the system's capabilities but also addressing a skills deficit through the establishment of a joint training center.

The HDX Extended System represents an invaluable tool for gaining insights into various aspects of protein science, including protein folding, conformational changes, binding interfaces, and the overall structural characteristics of individual proteins and large protein complexes.

On the significance of this collaboration between Trajan and Monash University, Associate Professor Ralf Schittenhelm, Scientific Director of MPMP, shared “There is a clear need for Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) in Australia as it is a powerful technique that provides insight into protein structure and dynamics.”

He also underscored the far-reaching impact of this collaboration, stating, "We are very keen to provide structural biologists access to this technology. We have received quite a few requests about HDX and with this collaboration, we are able to now bridge this gap and fulfill a demand/user-driven development."

Dr. Robert Ninnis, Trajan's Business Manager - Automation, ANZ, shared insights into the future aspirations of this collaboration. He emphasized the intention to extend access and knowledge-sharing to other researchers keen on harnessing the potential of HDX technology.

Dr. Ninnis articulated Trajan's strategic investment in Monash University as a research partner with the skills and passion necessary to propel HDX within the Australian research landscape. The establishment of the training center holds the key to addressing the skills deficit and positions itself as a pivotal step toward the future of HDX in the global scientific community.

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