High-throughput, high sensitivity and low carryover: the new infusion automation from Trajan offers you everything you need to bring your lipidomics mass spec workflow to its peak performance.
Move from manual sample infusion to the highest standard of infusion automation. With rapid cleanup between injections and best-in-class software architecture to integrate into your workflow, our infusion automation will elevate your lipidomics experiments.
The most consistent and flexible system available for infusion automation
Fully customizable infusion eliminates carryover concerns while saving you time. Allows for sample infusion at flow rates between 5 and 100 µL/min — directly into your ESI source via the injection valve — precisely and without pulsation. Compatible with both shotgun and targeted lipid analysis.
The powerful Chronos software can execute important operational and integration functions such as reading and reporting to LIMS software, as well as MS acquisition mode switching within a single infusion. The system maintains flow to the source while quickly and thoroughly washing the syringe system for the next infusion.
Exclusive inert configuration is available for your trickiest lipid classes — ensuring your samples never come into contact with any polymers.
“We just ran a whole pile of samples. It ran 24/7 without a hitch. Very reliable.” - Calvin Vary, PhD, Proteomics and Lipidomics Core Facility Maine Medical Center Research Institute, Maine, USA.
Upgrade sample throughput without worrying about carryover
The LEAP PAL injector head is a syringe pump itself, making it the ideal sample delivery system for ESI flow rates, unlike conventional HPLC pumps.
Many lipids are notorious for their adherence to glass and other surfaces resulting in carryover between samples. The special LCMS syringe tool incorporates unique features to minimize this carryover to below 1% for the abundant neutral and phospholipids and even lower for other species.
The illustration below shows how this rapid washing is achieved. After washing the inside, the system will wash the needle externally and be ready to aspirate the next sample.
Figure 1 Sample infusion
Greatest experiment control with powerful, user-friendly software
The infusion process is controlled using our Chronos software, allowing maximum compatibility with your preferred Chromatography Data System, LIMS and MS data systems.
Method parameters are available for flow rates, infusion times, stabilization delays and cleanup conditions, MS acquisition method switching.
With an optional second valve, standard chromatography methods can be used in the same sequence with direct infusion samples.
Figure 2 An example Chronos infusion method
|Flow rate range||5-100 μL/min.|
|Sample formats||Sealed and unsealed vials (1 mL, 2 mL, 10 mL); sealed and unsealed plates (96 and 384-well).|
|Optional features||Sample cooling drawers (4-40°C), inert flow path, second valve for chromatography autosampling|
|Sample capacity||Expandable capacity, from three plate tray holder, to 6 or 12 plate drawer stack(s). Capacity depends on vial/tray formats and drawer configuration, maximum 4 stacks|
|Signal stability||Signal stability on a single sample has been demonstrated for 20 minutes. Long term stability confirmed in successful analysis of 400 samples over a 36 hour period (5 minute injection per sample).|
|Computer requirements (minimum)||Operating system: Windows 7 SP1 (32 or 64 bit), Windows 8.1 or Windows 10. Hardware: Intel Dual Core 2.0 GHz, 60 GB hard disk, 4 GB RAM, dedicated ethernet port or free location on local private network switch with 1 free USB port for security dongle. Monitor: 1366 x 768 (recommended 1440 x 900 or 1920 x 1080).|
The newly updated LEAP NMR prepstation is a modular solution designed to help you improve your sample preparation workflow.
From basic workflows...
To complex sample handling...
View full product details
Powered by Chronos, the NMR prepstation can be configured as a walk-up, push button system, or allow the user to build custom sequences in the full software interface.
The LEAP CHRONECT® Quantos integrated powder-liquid automation system is a complete workflow like no other. This powerful platform is achieved through seamless coordination of industry proven, trusted, modular elements.
The high-precision, safe and reliable powder automation you’ve always wanted.
Integration of accurate dosing and weighing technology into liquid sample preparation maximizes your time and resources while minimizing user exposure and error sources.
The most complete, trusted and flexible system available
The industry-leading Quantos powder dosing capability, from METTLER TOLEDO, enables the highest level of accuracy and safety in powder delivery. The calibrated and certified balance is isolated from the moving components through optimized mass and mechanical damping. The integrated, multi-axis, cooperative robot combined with the precision-engineered platform facilitates the automation of up to 32 different powders.
Synchronized and in parallel, the PAL workstation automatically seals and caps vials, adds accurate liquid volumes, agitates, vortexes, mixes, heats, and or promotes dissolution or extraction from the solid, according to your workflow.
Positive tracking and traceability of powder dosing heads through RFID
Positive tracking and traceability of powder dosing heads is achieved through embedded RFID tracking. This tracking and workflow information can be output directly to LIMS systems, data systems, PDF, Excel or CSV formats.
The powerful Chronos software empowers users with familiar sample/method based control. The Chronos software natively drives all modules in the system, eliminating any need for robot programming in your laboratory. Chronos also expands compatibility to integration with large scale automation systems, all major analytical instrument data systems, and legacy QX96 excel files.
Compact footprint allows you to handle powder samples in a safe, inert gas environment
The integrated system is designed with your lab in mind, and a footprint compatible with benchtop, open laboratory environments and both positive and negative pressure cabinets.
Powder can be added to vials in a completely isolated environment, sealed in inert gas, and prepared for any analytical technique, without users coming into contact with potentially toxic or otherwise hazardous powders.
Sample and dosing
Powder dispensing range: 1 mg - several grams.
Component dosing heads: Up to 32 Quantos standard dosing heads.
Suitable powders: Free-flowing, fluffy, granular or electrostatically charged.
Dispensing time - 1 component: 10 - 60 seconds, depending on compound.
Target vial formats: Sealed and unsealed vials (2 mL, 10 mL, 20 mL); unsealed 1 mL vials.
Dimensions (w x d x h):
- without capping or liquid prep: 950 mm x 650 mm x 825 mm
- with capping and/or liquid prep: 1575 mm x 795 mm x 825 mm
CHRONECT robot: cooperative robot and Quantos platform.
Quantos powder dosing: automated analytical balance and dosing module.
Capping/liquid automation: PAL system and Chronos control software - varies by application.
The PAL3 System is one of the most widely used and successful sample preparation and handling platforms.
PAL System’s new generation of sample preparation and handling instruments.
This kit comes with 10 caps and 10 seals to fit 100-WV solvent bottles or PAL WashStd1 solvent vials.
These caps work with both PAL3 autosampler and xt-system bottles and vials.View full product details
One-piece tension cord (also referred to as bungee cord) for PAL-xt models and earlier.
Two sizes are available, 90 mm and 280 mm, and both should purchased at the same time.
It is recommended to replace the tension cords annually, as part of your preventative maintenance program. The cords should also be replaced if you notice your xt or legacy model PAL autosampler has started to bend syringe needles.View full product details
CERTUS FLEX is a modular system in two basic versions, with 5 or 8 individually controllable channels. These channels can be equipped with different valves to facilitate ideal dispensing of substances with different physical properties.
Unparalleled accuracy, precision and flexibility
The CERTUS FLEX has been developed for contactless dispensing of a broad range of liquid substances and large molecules, using Gyger's renowned microvalve technology and air pressure control, giving you maximum precision and flexibility.
Flexible fluid uptake options to meet your exact needs
Fluids can be supplied to the dispenser from bottles and tubes for bulk dispensing, or from syringes to achieve the lowest dead volumes. This allows you to more effectively dispense smaller volumes and high value substances from luer-lock syringes (from 3 - 60 mL).
Unique microvalves for more dispensing operations, with less dead volume
Over 500 million cycles without losing accuracy.
The CERTUS FLEX liquid dispenser delivers volumes in single doses, in contrast to many other techniques, allowing you to have the fastest delivery and the longest valve life. With an assortment of valve sizes, you can dispense a wide range of fluid types:
SiLA compliant for seamless process integration
Our SiLA automation interface allows you to integrate your CERTUS FLEX into your laboratory automation workflow with confidence. Drivers are already available for most major integration software, and more are being developed all the time.
CERTUS CONTROL PC software is both intuitive and easy to program
With a windows-based user interface, the CERTUS CONTROL software has a familiar look and feel, making everyday use straightforward. Both basic and complex dispense patterns can be created, with the software, or by importing CSV, to allow the Flex to compliment your workflow seamlessly.
Service you can trust
Our Gyger manufacturer-certified service team is ready to keep your CERTUS FLEX at its peak performance.
We have the expertise and experience with microdispensing across many different laboratory environments. We can guide you to the best system set-up and protocols for your laboratory's workflows.
Replacement bottle kits (bottles or conical tubes) and components for your CERTUS FLEX liquid dispenser. Kits are best used for high-throughput and larger volume dispensing, as well as applications where fluids will be set up on the system for extended periods.
All materials are autoclave safe and compatible with most fluids, including DMSO (see specifications below).
Bottle head materials: PTFE, PEEK, FKM, stainless steel
Tubing kit: 700 mm length FEP tubing (1.58 mm ID, 3.17 mm OD), FFKM/FFPM o-ring, SS connector, PEEK male nut, Tefzel/steel ferrule.
Immersion filter materials: Stainless steel body, PEEK cap, 37μ mesh SS filterView full product details
Replacement syringe kits and components for your CERTUS FLEX liquid dispenser. Kits are best used for precious fluid dispensing and applications where low dead volume is critical.
All materials are autoclave safe and compatible with most fluids, including DMSO (see specifications below).
Syringe adapter materials: PEEK, FPM o-ring
Disposable syringe material: Polypropylene (PP)
Luer lock channel inlet adapter materials: Stainless steel, FFKM/FFPM o-ringView full product details
Gyger SMLD 300GC microvalves are the core technology of the CERTUS FLEX liquid dispensers.
The microvalves are made of the following materials: Stainless Steels 1.4404 (A316L), 1.4301 (A301), 1.4310 (A304), 1.4113 IM / 1.4105 IL (A430F); PEEK, sapphire, ruby.
Microvalve selection is based on the properties of the fluids you plan to dispense, the volumes you wish to dispense, and the plate format you intend to use. Use the following table as a general guide, or reach out to have our experts help you pick the perfect one.
With the proper use and cleaning of your valves, they should last 6 months to a year. After dispensing acidic, sticky or crystallizing substances, the microvalves should be thoroughly flushed immediately after use. Additionally, you may sonicate your valves, backflush them, and autoclave them, as your needs require.
?Estimated lead time is 1-2 weeks.View full product details
The CERTUS FLEX microvalve cleaning kit enables the backflushing and detailed cleaning of CERTUS FLEX liquid dispenser valves.
The microvalve is placed in the valve holder (1) where it can be backflushed using a syringe (2) to push any particles in reverse. The PEEK Luer Lock adapters (3) allow easy changes from syringes to tubing (4), which enables the tool to be used in a sonicating bath for a more intense clean. The kit also comes with a Torx key (T10).
Kit: Valve holder, 2 x syringes, 2 x PEEK Luer Lock adapters, tubing, Torx key.View full product details
These CTC Analytics stainless steel sample loops are designed for HPLC and UHPLC applications using Cheminert valves.
Stainless steel sample loops, with 1/16" stainless steel nuts and ferrules.
These loops are cut electrolytically and polished for square, burr-free ends. They are steam cleaned with filtered, deionized water.
Sample loops are accurately sized for each valve type. However, with small volume loops the tolerance on the ID of the tubing (±0.001") can have a significant effect on the volume. Therefore loop volume and loop appearance may differ from batch to batch.
For North America. Estimated lead time is 14-21 business days.